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The researchers also found that the reduction in LFC was related to the amount of fat in the liver at the beginning of the study, as well as reductions in VAT, ASAT, and body weight in the tirzepatide groups

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In a subanalysis of SURPASS-3, tirzepatide 10 and 15 mg resulted also in a relative reduction in liver fat content by 4047% compared to 11% with insulin glargine at 52 weeks [44]

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When L-carnitine was stopped, asthenia resumed within 15 to 30 days

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