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The association of DPP-4 with osteoclasts suggests a stimulatory action of this enzyme on bone resorption [3, 4], potentially affecting bone mineral density (BMD) and fracture risk and identifying DPP-4 activity as a potential marker of altered bone metabolism [5,6,7,8,9,10]

Pearsons correlation coefficient (Pearsons r ) or Spearmans rank correlation coefficient were calculated to assess the linear correlations between variables with a normal or non-normal distribution, respectively

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If sleep problems persist despite optimizing all the factors within your control, consultation with a sleep medicine specialist may be warranted