Infant example: Consider consultation with local paediatric team when Admission should be considered for all children and young people with an intentional overdose Consult the Poisons Information Centre 13 11 26 for advice Consider transfer when Children requiring care beyond the comfort level of the hospital For emergency advice and paediatric or neonatal ICU transfers, see Retrieval Services Consider discharge when No further acetylcysteine requirement and investigations are within normal limits (see Monitoring section) For deliberate ingestions, a risk assessment should indicate that the patient is at low risk of further self-harm in the discharge setting Assessing risk and connecting to community services Prior to discharge, adolescents who present with deliberate ingestions need a risk assessment regarding the likelihood of further ingestions or other attempts to self-harm Assessment of other drug and alcohol use should also be undertaken If, after risk assessment, it is deemed safe to discharge a child or adolescent from hospital, but ongoing mental health or drug and alcohol needs are identified, they should be linked with appropriate services Parent information Poisoning prevention for children Additional resources Poisons Information Centre Phone 131126 New South Wales: Queensland: Victoria: Mental Health, Drug and Alcohol Services: New South Wales Child and Adolescent Mental Health Services: services delivered across NSW Health with referrals made via the NSW Mental Health Line (1800 011 511) for 24-hour advice, assessment referral information Youth Health and Wellbeing: includes links to Assessment Guideline for providers caring for young people aged 12 24 years across settings, as well as links to other resources Your room: information on alcohol and other drug use, including fact sheets (multiple languages), assessment tools and links to support services Queensland Child and Youth Mental Health Services: specialise in helping infants, children and young people up to age 18 years with complex mental health needs Dovetail: provides clinical advice and professional support to workers, services and communities who engage with young people affected by alcohol and other drug use Queensland Youth AOD Services Guide: created by Dovetail, this guide provides an overview of youth alcohol and other drug treatment services across Queensland

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J Clin Invest (1987) 79(2):6169.10.1172/JCI112855 4 SasakiSMiyatsukaTMatsuokaTATakaharaMYamamotoYYasudaTet alActivation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice