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Journal of Clinical Endocrinology and Metabolism 2021

By stimulating glucose-dependent insulin secretion and suppressing glucagon production, they are a cornerstone of the treatment of type 2 diabetes (DM2), particularly in patients with a higher risk of cardiovascular disease ( This narrative review describes the complex interplay between GLP-1 signalling and intestinal inflammation, highlighting both the potential benefits and limitations of GLP1 RAs in IBD management, with a particular focus on their promising role in selected obese IBD patients

Practical considerations for men Unlike women, men rarely use oral testosterone (the oral form has bioavailability issues independent of GLP-1 effects)

Categorical variables were reported as frequencies and percentages, normally distributed continuous variables were described as the mean standard deviation, and non-normally distributed continuous variables were described as median (interquartile range)