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Routine monitoring should include discussing any new or changed symptoms at your regular diabetes or weight management reviews

Patients should contact their GP or healthcare provider if they experience: Persistent vomiting preventing adequate fluid or food intake Severe or persistent abdominal pain (potential pancreatitis) Signs of dehydration (dark urine, dizziness, reduced urine output) Unexplained weight loss exceeding expected therapeutic effects Any symptoms suggestive of ketoacidosis as previously described Immediate medical attention (A&E or 999) is warranted for: Severe abdominal pain with vomiting Confusion or reduced consciousness Rapid breathing with fruity breath odour Blood ketone levels 3.0 mmol/L Inability to keep down fluids for more than 12 hours Patients planning surgery should discuss Mounjaro with their surgical/anaesthetic team, as some centres may advise withholding weekly GLP-1 receptor agonists pre-procedure due to delayed gastric emptying effects

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