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First identified in 1977 from cerebral venous blood of rabbits during electrically induced sleep by Swiss researchers Schoenenberger and Monnier, DSIP has since been studied for its role in sleep architecture regulation, stress response modulation, and neuroendocrine activity

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We performed univariable and multivariable Cox proportional hazard regression analyses to calculate the hazard ratio (HR) and 95% confidence interval (CI) for incident HTN according to OBS quartiles