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Results Differential balance between excitatory and inhibitory neurotransmitters in healthy and OCD brain Figure 1 shows the positive relationships between Glu and GABA in the ACC for the OCD and healthy subjects separately (OCD + healthy subjects: Pearsons r = 0.51, p = 0.00003, p -FDR = 0.0002), whereas only healthy volunteers showed a positive relationship in SMA (Pearsons r = 0.37, p = 0.04, p -FDR = 0.05) and OCC (Pearsons r = 0.46, p = 0.01, p -FDR = 0.01)

In models of retinal degeneration, Epitalon has been delivered via parabulbar injection, a technique that places the compound near the posterior eye to maximize local availability [64, 65]

Following a 5 mg single oral dose of saxagliptin to healthy subjects, the mean plasma AUC values for saxagliptin and its active metabolite were 78 ngh/mL and 214 ngh/mL, respectively

Can J Physiol Pharmacol 98(2):5160