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Using data records from the NHS up until 2016, the researchers could identify which of the sample donors went on to develop one of 30 different types of malignant cancers, within an average period of seven years

Furthermore, visual inspection of the funnel plot revealed the asymmetric distribution (online Supplementary Fig

Furthermore, studies on serum from SZ patients showed elevated levels of polyamine oxidase (the enzyme responsible for degrading PAs) (96, 97), while the activities of three enzymes involved in PA synthesisornithine aminotransferase, antizyme inhibitor 1 (AZIN1), and ornithine cyclodeaminase were found to be reduced in the prefrontal cortex of both treated and untreated patients (98), ultimately potentially leading to disrupted polyamine homeostasis

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