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Retatrutides Phase 2 trial showed 24.2% weight loss at 48 weeks for the 12mg dose

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35 36 Among the included studies, three used high-volume polyethylene glycol (PEG), 13 , 14 , 18 two used low-volume PEG, 14 , 18 and two employed magnesium- or phosphate-based regimens

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