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Also remember that while trying to stop smoking, the hardest part comes in the first three days, but by the end of five days the majority of individuals find the craving significantly reduced or gone

Sex differences in varenicline efficacy for smoking cessation: a meta-analysis

this excluded endpoints of smoking cessation, perceptions, attitudes, effects on the women, and cost of interventions (note that as discussed below, the RCTs were really only useful as studies of smoking cessation, but reported birth-outcome statistics so were included), Studies that did not appear in an academic journal, could not be found or were not reported in English, Swedish, Danish, or Norwegian

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