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[35] Although the mechanism is not very clear, the polyglutamylation of methotrexate and dihydrofolate in malignant cells is considered to play an important role in the selective reactivation of dihydrofolate reductase by folinic acid in normal cells

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This is especially critical for ultra-pure water systems, where it is mandatory to select high-purity caustic soda produced via the ion-membrane method, strictly controlling the content of impurities such as sodium chloride and iron ions

Participants completed pre- and posttests measuring their cancer knowledge, as well as Likert-scale items and short answers regarding their perspectives