Although a Statistics Canada population survey published in 2013 found, on average, seniors had only slightly lower levels of B12 than younger adults
However, there are some common indicators that it might be time to consider maintenance doses
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A second 2017 review in Clinical, Cosmetic and Investigational Dermatology by Iriarte and colleagues at George Washington catalogued the same expanding evidence base across acne scars, alopecia, melasma, photoaging, and drug delivery (Iriarte et al., 2017)