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Une supplmentation, sur prescription mdicale , est galement ncessaire : En cas de dficit hrditaire (trs rare) ou conscutif une maladie du foie (altrant sa production) ou des reins (augmentant les pertes, notamment en cas dhmodialyse)

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While positive airway pressure (PAP) is effective in keeping the upper airway open during sleep in individuals with moderate to severe OSA, about 30% to 50% of patients will discontinue PAP within the first year due to the cumbersome and uncomfortable nature of the device

10.1016/j.cub.2017.09.019 50 Van RongenA.VlitaloP