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Glucose conjugation facilitates GLUT1-mediated transport across the BBB, resulting in increased neuronal uptake and pronounced neuroprotective effects (103)

Notably, OG treatment shifted macrophage polarization toward an anti-inflammatory M2 phenotype and increased mitochondrial activity, facilitating adipose tissue remodeling and enhancing energy expenditure and thermogenesis

In the brain, free radicals activate microglial cells, the resident immune cells of the central nervous system

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