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NHS treatment is typically initiated and supervised by specialist weight management services, with specific duration limits (up to 2 years for semaglutide) and continuation criteria based on weight loss targets

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Theyre ideal for areas that dont respond to diet and exercise alone

the co-culture of MSCs and NP-cells increased the expression of anabolic GFs by MSCs, differentiation towards the discogenic lineage, and improvement of the NP cell phenotype through MSCs-NP cell communication, which was possibly mediated by the bi-directional intercellular transfer of membrane components [137,138]