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Epidemiology studies of IR Sex difference Different investigations have indicated that premenopausal women exhibit many less metabolic disorders than men, including lower incidence of IR, although this effect diminishes severely when women reach the postmenopausal situation

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JAMA 305 (21), 21842192

Experimental and epidemiological research has associated low glutathione levels with a range of conditionssuch as metabolic disorders, chronic infections, and various degenerative statesmaking glutathione a candidate biomarker for disease severity and progression in some studies