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One impact of the plant (main constituents are harmine and harmaline ) is that it increases GLP-1 in the hippocampus.[ref] Lithium: Lithium carbonate seems to suppress food intake (in some people) by activating GLP-1

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Life Sci 76:11231134 Santofimia-Castao P, Clea Ruy D, Garcia-Sanchez L, Jimenez-Blasco D, Fernandez-Bermejo M, Bolaos JP, Salido GM, Gonzalez A (2015a) Melatonin induces the expression of Nrf2-regulated antioxidant enzymes via PKC and Ca2+ influx activation in mouse pancreatic acinar cells