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Talk to your doctor before starting if you: Are allergic to B12 Have optic nerve issues (optic atrophy) Have blood in urine or polycythemia Are pregnant, breastfeeding, or trying to conceive Have low iron or folate, or an active infection Dosage, Concentration, Route of Administration Dosage: Always follow the guidance of a licensed medical provider for the correct dosage

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Intranasal bioavailability to the CNS is 3060%, compared to 1020% systemic bioavailability