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Therefore, these observations suggest that downregulating the expression and activity of the aforementioned proteins associated with melanosome transport may be useful for reversing the process of skin hyperpigmentation

doi: 10.3390/biom10010040 42 NyakasCGranicIHalmyLGBanerjeePLuitenPG

Evidence from randomized controlled trials and meta-analyses indicates potential improvements in fasting plasma glucose, glycated hemoglobin, insulin resistance indices, and inflammatory biomarkers, although heterogeneity in formulation composition, intervention duration, dosing strategy, and background pharmacotherapy attenuates certainty of effect

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