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Tran PT, Berman HS, Leavitt E, Hogeling M, Cheng CE

It works by interacting with molecular pathways to reduce elevated levels of pro-inflammatory cytokines

The efficacy of a second-generation derivative, omaveloxolone (RTA408), has recently been assessed in a preclinical model for diabetic chronic non-healing wounds [277] and, interestingly, omaveloxolone is now being tested in phase-II clinical trial for the Friedreichs ataxia (FRDA), a neurodegenerative condition in which NRF2 activation is suppressed [278, 279]

A 0.5 mL (50 unit) insulin syringe has finer gradation marks, making doses below 25 units easier to measure