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Using differential centrifugation, exosomes were isolated from the plasma of SD rats and loaded with SIN, resulting in Exo-SIN with a particle size of 90 4 nm (155)

10.1016/j.jbc.2022.101753 111 LiX.ZhuH.SunW.YangX.NieQ.FangX

940 TQCN treatment may improve numerous neurodegenerative diseases related with brain iron accumulation and ameliorate severe cognitive impairment in AD mice due to its multiplex modulation of the pathogenic process that triggers ferroptosis

Prebiotic supplementation (inulin, resistant starch) selectively enriches SCFA-producers, potentially rebalancing tryptophan metabolism toward protective indole derivatives (150, 151)