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Thalassemia affects how the body makes hemoglobin, leading to nutritional issues like Vitamin B12 deficiency

13 It is reported that between one-third and one-half of all patients with a non-melanoma skin cancer will develop another malignancy within five years

Bulboac AE, Porfire A, Bolboac SD, Nicula CA, Fetil DG, Roman A, et al

Baseline liver enzyme assessment is reasonable for patients with: Pre-existing liver disease or elevated baseline transaminases Metabolic syndrome or clinical features suggesting MASLD Concurrent use of other potentially hepatotoxic medications Obesity (BMI 30 kg/m) with additional metabolic risk factors History of excessive alcohol consumption For patients with abnormal baseline liver enzymes, periodic monitoring every 3-6 months during the first year of therapy allows clinicians to assess treatment response and detect any unexpected changes