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GLP-1 RAs improve CV outcomes, as well as secondary outcomes such as progression of renal disease, in patients with established CV disease or chronic kidney disease (CKD)
Human studies indicate that the insulinotropic action of GIP is blunted in individuals with severe hyperglycemia, in contrast to the intact action of GLP-1
What it does offer is consistent, systemic support that may help the body adapt more efficiently to physical, digestive, and inflammatory stressors over time
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