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Glutathione GSH [1] - [2] DNA [] - L- L-- (GCL) [3] -C GCLCGSH [4] [5] [6] [] R-SH 0.5 10 mmol/L [6] 90% GSHGSSG [7] 80-85% GSH10-15% [8] [9] [10] [11] [12] N- (NAC) GSH [13] RiboCeine [14] [15] [] GSH)GSSG [16] [8] [17] GSSG GSH (GSSG)NADPH [18] (GSH) NADPH + GSSG + H 2 O 2 GSH + NADP + + OH [] [] GSH [6] [19] 2 GSH + R 2 O 2 GSSG + 2 ROH (R = , ) GSH + R 1/2 GSSG + RH GSH [20] [] S- (RSH) GSH [21] RSH + GSH + [O] GSSR + H 2 O CE [22] [23] [24] GSH GSH [25] [] GSHI (EC 4.4.1.5) S -D-II (EC 3.1.2.6) S -D-D- [26] GSH [27] [28] S- (GST) GSH [29] [] GSHGSH MRS GSH GSH [30] [31] GSH [32] [33] [34] GSH [29] [] [35] [36] S- [37] [] S- [38] N -- p -(NAPQI) NAPQI P450() NAPQI [] - [39] [40] [41] [42] [] [] GSH [43] [] [44] UPLC-MRM [45] [] [] GSHGSH [46] [] [] ^ 1.0 1.1 1.2 CRC Handbook of Chemistry and Physics 97th