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All patients gave a written informed consent and the human sample collection was approved by the Ethics Committee of Zhongshan Hospital, Fudan University

Insulin and blood glucose concentrations decreased remarkably during the fasting period as shown in Table 4

While some people begin to see results within the first eight weeks, most start to see improvements after 12 weeks of Semaglutide GLP-1 treatment

The results revealed that the protein expression levels of ADRB2, BCL3, EGR1, FOS, MAP3K8, and apoptosis-related markers were significantly higher in the Model group rats compared to the Blank group rats