In 2025, crucial safety data regarding semaglutide was disclosed
4.2.1 Chemical drug-induced liver injury Glycyrrhizin activates the -catenin signaling pathway, upregulates proliferation-related proteins (such as Proliferating Cell Nuclear Antigen (PCNA), Cyclin D1, and Cyclin-Dependent Kinase (CDK) 4), promotes hepatocyte proliferation and liver tissue regeneration, thereby effectively alleviating acetaminophen-induced acute liver injury and significantly reducing acetaminophen (APAP)-elevated serum ALT and AST levels (Li et al., 2022)
Springer, New Delhi Wang H, Zou Z, Wang S, Gong M (2014) Deep sequencing-based transcriptome analysis of the oil-bearing plant physic Nut (' Jatropha curcas L.) under cold stress
At second place was Jubilant Biosys 21 CEPs were revised in Q1 2026.In terms of products, the maximum CEPs were issued for amlodipine besylate (a calcium channel blocker used for treating hypertension), followed by sitagliptin phosphate (a type 2 diabetes medicine) and pregabalin (a drug used to treat neuropathic pain, fibromyalgia, seizures, and generalized anxiety disorder)