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The full dose may be taken once in the morning on an empty stomach, or split into two to three daily doses throughout the day, each on an empty stomach

If it impacts the testicular microenvironment, it could enhance sperm count or motility, but data are limited and the mechanism is different than how it might act in ovaries or endometrium

These were ex-vivo permeation experiments framed around anti-inflammatory delivery rather than wrinkle outcomes, so they speak to whether the molecule can reach the dermis, not to how much cosmetic change follows but even that limited, mechanism-level demonstration is one the injectable route has no equivalent of for reaching skin specifically