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In a clinical study involving 1,651,452 patients with type 2 diabetes, semaglutide decreased the development of 10 out of 13 obesity-associated cancers, which include the following: Colorectal cancer Meningioma Endometrial cancer Gallbladder cancer Multiple myeloma Kidney cancer Ovarian cancer Pancreatic cancer Esophageal cancer Hepatocellular carcinoma These results suggest that GLP-1 receptor agonists can protect against cancer

Nonetheless, further randomized controlled trials of sirolimus in SLE are warranted

Barnhill MS, Steinberg JM, Jennings JJ, Lewis JH (2020) Hepatotoxicty of agents used in the management of inflammatory bowel disease: a 2020 update

But more prescriptions are not the same as better outcomes, and without wraparound clinical care the UK risks turning a major breakthrough into a short-term consumer market and missing out on a huge public health opportunity