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A subsequent study indicated that its therapeutic effects are also associated with a reduction in oxidative stress biomarkers (90)

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At the level of the isolated spermatozoon, ROS attack can induce lipid peroxidation and DNA fragmentation disrupting both the motility of these cells and their ability to support normal embryonic development.176182 At the level of the testes, oxidative stress is capable of disrupting the steroidogenic capacity of Leydig cells183 as well as the capacity of the germinal epithelium to differentiate normal spermatozoa.184 A large number of independent clinical studies have demonstrated a correlative relationship between male infertility and evidence of oxidative stress in the ejaculate.180,185 Moreover the literature reviewed in this chapter reveals an abundance of experimental data in animal models demonstrating a causal relationship between the induction of oxidative stress in the testes and the impairment of male reproductive function

BPC-157 works systemically , meaning it spreads through your body regardless , but local injection delivers a higher concentration directly to the tissue that needs it