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Thus, an increase in NRF2 activity, reflected by induction of NRF2 target genes, likely represent an important mechanism mediating the protection seen in GCLM KO mice

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In this sense, two commercial rumen-protect Met products are particularly popular in animal production, namely Mepron M85 (Evonik Nutrition and Care GmbH, Hanau-Wolfgang, Germany) and Smartamine - M (Adisseo Inc., Antony, France)