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Proline (Pro) In 1900, proline was chemically synthesized

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For example, C-Myc amplified in ovarian cancer cells inhibits ferroptosis by inducing NCOA4-mediated ferritinophagy [94] , but erastin selectively kills iron-addicted ovarian cancer cells by inducing ferroptosis and promoting NCOA4-mediated ferritinophagy and mitochondrial dysfunction [95]

Although we identified the potential for certain antioxidants such as pycnogenol and L-arginine, they were often components of combination products such that determining the treatment effect of individual components was not possible